At present, the mass vaccination of new coronavirus vaccine continues to be popularized, and the injection of booster is becoming more and more popular. However, the global epidemic is still continuing and repeated, and the number of infection cases and death cases of new coronavirus continue to rise. Among them, the re infection cases of infected and cured patients after complete vaccination have attracted extensive attention.
As we all know, the main purpose of vaccination is to effectively prevent infection, severe illness and death, but no vaccine can provide 100% immune protection. Among them, the infection after full dose vaccination is called breakthrough infection.
With regard to breakthrough infection, it is now possible to confirm that compared with those who have not been vaccinated and infected with COVID-19, people who have breakthrough infections after full dose vaccination are less likely to suffer from severe illness, and the possibility of hospitalization or death is much smaller. Data from the Centers for Disease Control and Prevention (CDC) show that vaccinated people are 8 times less likely to infect the new crown than non vaccinated people, and 25 times less likely to be seriously hospitalized or die; Data in the UK have shown that there is one breakthrough infection case per 500 people vaccinated with full dose vaccine.
Now, a new study examines the intensity, persistence and breadth of neutralizing antibody responses to breakthrough infections in people vaccinated with the new coronavirus vaccine.
The results showed that novel coronavirus pneumonia vaccine was successfully completed in the study group, and those who completed the three dose vaccination program, and those who recovered from the new crown pneumonia infection, and those who had breakthrough infections after vaccination, started almost the same antibody response in size and breadth. Their serum binding and antibody neutralization response to the spike protein in the current pandemic coronavirus variant is much stronger and more lasting than those who have only received two doses of new coronavirus vaccine or those who have not been vaccinated before.
That is to say, through infection and vaccination or three doses of vaccine, the human body can increase the number of exposure to COVID-19 antigens and improve the quality of the antibody response.
In addition, the researchers also observed the universality of the stimulated antibodies. The researchers studied the neutralization of Omicron variants. The results showed that the neutralizing antibody levels of individuals inoculated with booster needles were similar to those of subjects inoculated twice against the original strain. This indicates a large number of immune escapes, but vaccine booster shots can help narrow the neutralizing antibody gap caused by Omicron.
As Zhang Wenhong said, the vaccine is the real strength to fight the virus. At present, Omicron is still widely popular. In order to obtain the real confidence against the virus, it is still urgent to strengthen the injection of the new coronavirus vaccine.
